The Boxtrolls have raised an orphaned human boy, Eggs, since infancy as one of their dumpster-diving and mechanical junk-collecting own. When the Boxtrolls are targeted by villainous pest exterminator Archibald Snatcher, who is bent on eradicating them as his ticket to Cheesebridge society, the kindhearted band of tinkerers must turn to their adopted charge and adventurous rich girl Winnie to bridge two worlds amidst the winds of change - and cheese.